As the experts in digestive and metabolic medicine and as a family-owned business with a global presence, we focus on developing and marketing innovative medicines to treat a wide range of gastrointestinal disorders like inflammatory bowel disease or eosinophilic esophagitis as well as hepatobiliary disorders such as primary biliary cholangitis. Our aim: to meaningfully improve therapeutic practice as well as patient health and well-being. We firmly believe that medical progress can only be achieved by working together. That is why we are looking for:
Principal Scientist Pharmacology (m/f/d)
Your tasks
As Principal Scientist Pharmacology, you will strengthen our Preclinical and Early Clinical Research team by providing scientific leadership across our research and development portfolio. In this strategic and highly visible role, you will guide translational and clinical pharmacology activities, support key regulatory and development decisions, and help shape the future direction of our pipeline.
Key responsibilities
- Oversee the clinical pharmacology and translational strategy across multiple drug development programs
- Provide scientific support and advice to our preclinical and early clinical development teams in the design, execution and interpretation of pharmacology studies and PK/PD analyses
- Drive the translation of preclinical findings into clinical development strategies and support the definition of clinical treatment parameters
- Identify scientific opportunities, development risks, and key decision points to inform pipeline prioritization and development planning
- Represent the department in cross-functional teams, external collaborations, and scientific interactions, providing expertise in translational and clinical pharmacology
- Provide strategic and scientific support for regulatory interactions, including scientific advice procedures, deficiency letters and regulatory submissions
- Serve as a clinical pharmacology expert on governance bodies, including Data Monitoring Committees, Data and Safety Monitoring Boards and scientific advisory boards
- Contribute to innovative drug development through scientific and strategic assessment of new product candidates and development opportunities
- Build and maintain scientific networks with external experts, academic collaborators, and contract research organizations
Your qualification
- PhD, PharmD, MD, or equivalent advanced degree in Pharmacology, Clinical Pharmacology, Pharmaceutical Sciences, Biochemistry, or a related life science discipline
- More than 5 years of relevant pharmaceutical or biotechnology industry experience in drug development, translational research, clinical pharmacology, or related fields
- Demonstrated expertise in clinical pharmacology, translational science, and mechanism-based drug development
- Hands-on expertise in population pharmacokinetic (PopPK) and physiologically based pharmacokinetic (PBPK) modeling and simulation
- Demonstrated experience supporting regulatory submissions and interactions with health authorities
- Proven ability to evaluate and integrate complex scientific data to support strategic decision-making
- Strategic mindset with strong organizational and prioritization skills
- Collaborative team player with excellent inter-personal and communication skills
- Strong leadership capabilities
- Solution-oriented mindset with a high degree of flexibility, resilience, and adaptability
- Fluent written and spoken English; German language skills are considered an advantage
Your benefits
- Supportive, respectful and appreciative work atmosphere in a dedicated drug development team
- Diverse learning culture and individual development opportunities
- International and growing family business with short decision-making processes, financial independence and long-term perspective
- New work, flexible working hours and mobile working
- Wide range of benefits (free beverages, health and sports benefits, canteen, JobRad)
- Comprehensive onboarding and mentoring program